WebSpironolactone. Spironolactone is a powerful potassium-sparing diuretic that inhibits the binding of aldosterone to mineralocorticoid receptors in many tissues, including epithelial cells of the distal convoluted tubule and collecting duct. From: Comprehensive Medicinal Chemistry II, 2007. View all Topics. Web11 DESCRIPTION. ALDACTONE oral tablets contain 25 mg, 50 mg, or 100 mg of the aldosterone antagonist spironolactone, 17-hydroxy-7α-mercapto-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone acetate, which has …
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WebEplerenone, sold under the brand name Inspra, is an aldosterone antagonist type of potassium-sparing diuretic that is used to treat chronic heart failure and high blood pressure, particularly for patients with resistant hypertension due to elevated aldosterone.It is a steroidal antimineralocorticoid of the spirolactone group and a selective aldosterone … WebMar 14, 2024 · Aldactone Tablet is a medicine known as a diuretic (water pill). It is mainly used in the treatment of heart failure and high blood pressure. It reduces the swelling (edema) caused by some other conditions. This medicine is also used to treat low potassium levels in the body (hypokalemia). Aldactone Tablet should be taken with food at the … fire dispatch brooklyn
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WebLowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling ( edema) caused by certain conditions (such as heart failure, liver ... WebSpironolactone is not prescribed to treat acne in men due to side effects. Men have developed breasts while taking this medication to treat acne. Spironolactone is generally considered safe for healthy women. Taking both spironolactone and the pill can increase effectiveness. This combination has another advantage. WebGeneric Name Spironolactone DrugBank Accession Number DB00421 Background. Spironolactone is a potassium sparing diuretic like eplerenone that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. 8 Spironolactone was originally developed purely for … estimated number of slaves worldwide