WebJun 23, 2024 · Side Effects What are the side effects of Trientine (Syprine)?. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult … WebAug 1, 2024 · Trientine hydrochloride capsules should be used when continued treatment with penicillamine is no longer possible because of intolerable or life endangering side effects. Unlike penicillamine, trientine hydrochloride capsules are not recommended in cystinuria or rheumatoid arthritis.
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WebLess serious side effects Less serious side effects What to do Gastrointestinal related: • Nausea Other ingredients • Abdominal or stomach pain or discomfort Skin related: • Skin … WebBackground & aims: Wilson disease is a genetic copper storage disorder that causes hepatic and neurologic symptoms. Chelating agents (D-penicillamine, trientine) are used as first-line therapies for symptomatic patients, but there are few data from large cohorts. We assessed the safety of D-penicillamine and trientine therapy and outcomes of ... polyethylene glycol package size
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WebThis effect is more common in patients treated with D-penicillamine and up to 50% of WD patients with neurologic presentation experience further deterioration that is often irreversible. 78 The same phenomenon is also observed with trientine therapy but its incidence is lower with 10%–15% patients experiencing progression of their neurologic ... WebJul 25, 2024 · Trientine is an oral copper chelating agent used to treat Wilson disease. ... (Four patients with primary biliary cirrhosis and elevated hepatic copper levels developed intolerable side effects within two weeks … WebChelating agents. Penicillamine (Cupramine, Depen) and trientine (Syprine) are two chelating agents used to treat Wilson disease. These medicines remove copper from the body. Penicillamine is more likely to cause side effects than trientine. Side effects of penicillamine may include fever, rash, kidney problems, or bone marrow problems. polyethylene glycol pediatric dosing